Palace and Brighton meet for the first time in the Premier League at the Amex Stadium.
Hodgson knows the rivalry between the two clubs and said: “What changes with a derby is the pressure and expectation on everybody to not disappoint the fans, because the fans take the derby results a little bit harder if it does not go their way.
“I know the rivalry is very strong and dates back a long time. Every club has its derby match, we have several because we are a London club, but this one is regarded as the most important derby for the Palace fans and we are preparing for it accordingly.”
Palace are yet to pick up a single point away from home this season and Hodgson knows Brighton would be a great place to get their first win on the road.
Hodgson, who has no fresh injury concerns ahead of the game, said: “Winning away from home would be good, we have not even taken a point away from home.