The Reds take to the Estadio do Dragao looking to secure a vital win on their first knockout-stage clash in Europe’s top tier since 2009.
Having got back to winning ways away to Southampton on Sunday, Klopp’s side can hope to extend their unbeaten run to four games and secure an aggregate lead before the return leg at Anfield.
So how should Klopp line his Liverpool side up in Portugal?
The Reds’ XI vs. Porto
Can’s absence can be considered a blow given the German’s recent form, but Klopp has already catered for the problem by resting Henderson at the weekend.
The captain will take over in the No. 6 role, in what could be one of few changes on Wednesday.
The only point of contention at the back is whether Lovren or Joel Matip partners Van Dijk, but with the former also rested on…